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The Nature of NutritionA Unifying Framework from Animal Adaptation to Human Obesity$
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Stephen J. Simpson and David Raubenheimer

Print publication date: 2012

Print ISBN-13: 9780691145655

Published to Princeton Scholarship Online: October 2017

DOI: 10.23943/princeton/9780691145655.001.0001

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(p.194) Eleven Perspectives
The Nature of Nutrition

Stephen J. Simpson

David Raubenheimer

Princeton University Press

This concluding chapter looks at some of the big issues that remain in nutritional biology. Exploding protein into its constituent amino acids means having to deal with 19 extra dimensions, which is fine in theory but daunting in practice. However, such an expansion is what will be needed to understand the mechanisms of protein appetite, the role of protein in aging, obesity, and immune function, or the behavioral and metabolic consequences of replacing marine-based animal proteins with plant-derived alternatives in the diets of farmed fish. The next step will be to associate primary response variables such as life span, disease susceptibility, and fecundity with associated physiological, metabolic, and geometric responses. Other issues include nutritional epigenetics and early-life prevention of metabolic disease, human obesity, nutritional immunology, and modeling nutritional interactions.

Keywords:   nutritional biology, protein appetite, geometric responses, metabolic responses, nutritional epigenetics, metabolic disease, human obesity, nutritional immunology, nutritional interactions, physiological responses

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