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The Population Biology of Tuberculosis$
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Christopher Dye

Print publication date: 2015

Print ISBN-13: 9780691154626

Published to Princeton Scholarship Online: October 2017

DOI: 10.23943/princeton/9780691154626.001.0001

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PRINTED FROM PRINCETON SCHOLARSHIP ONLINE (www.princeton.universitypressscholarship.com). (c) Copyright Princeton University Press, 2021. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in PRSO for personal use.date: 21 September 2021

Interventions and Control

Interventions and Control

(p.100) Chapter 4 Interventions and Control
The Population Biology of Tuberculosis

Christopher Dye

Princeton University Press

This chapter considers a variety of tuberculosis control measures that can change the rates of transition between states of health. Without a better understanding of who is most at risk of infection and disease, the opportunities for targeted prevention and treatment are limited. This is why dominant TB control efforts today do not focus on hotspots but rather confront the disease in whole populations. The principal approach to TB control, drug treatment of active disease, has saved millions of lives but has been much less effective in stopping TB transmission. The chapter examines the effects of different approaches to TB control, current and future technologies, and the outcomes for infection, disease, and mortality. It shows that while the mitigation of risk factors such as diabetes, undernutrition, or tobacco smoking is helpful as an accessory to TB control, the greater opportunity for immediate impact lies with the early diagnosis and curative treatment of TB disease.

Keywords:   tuberculosis, risk, TB infection, TB prevention, TB control, drug treatment, TB transmission, risk factors, diagnosis, mortality

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