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Biomolecular Feedback Systems$
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Domitilla Del Vecchio and Richard M. Murray

Print publication date: 2014

Print ISBN-13: 9780691161532

Published to Princeton Scholarship Online: October 2017

DOI: 10.23943/princeton/9780691161532.001.0001

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PRINTED FROM PRINCETON SCHOLARSHIP ONLINE (www.princeton.universitypressscholarship.com). (c) Copyright Princeton University Press, 2022. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in PRSO for personal use.date: 29 May 2022

Dynamic Modeling of Core Processes

Dynamic Modeling of Core Processes

(p.29) Chapter 2 Dynamic Modeling of Core Processes
Biomolecular Feedback Systems

Domitilla Del Vecchio

Richard M. Murray

Princeton University Press

This chapter describes basic biological mechanisms in a way that can be represented by simple dynamical models. It begins with a discussion of the basic modeling formalisms that will be utilized to model biomolecular feedback systems. The focus in this chapter (as well as the next) is on deterministic models using ordinary differential equations. Here, the chapter proceeds to study a number of core processes within the cell, providing different model-based descriptions of the dynamics that will be used in later chapters to analyze and design biomolecular systems. In this chapter, emphasis is placed on dynamics with time scales measured in seconds to hours and mean behavior averaged across a large number of molecules.

Keywords:   biological mechanisms, biomolecular systems, simple dynamical models, basic modeling formalisms, deterministic models, differential equations, core processes, biomolecular feedback systems, time scales, mean behavior

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